What is Myasthenia Gravis? Myasthenia gravis (MG) is a chronic autoimmune neuromuscular condition that disrupts communication between nerves and muscles. In people with MG, this signalling process is disrupted, making it harder for muscles to respond. As a result, muscles become weak and tire more easily. MG primarily affects voluntary muscles (those under conscious control) particularly in the face, neck, arms and legs. Everyday functions such as moving the arms and legs, fa